RU-486 is used in early weeks of pregnancy. It is maximum effective till 9 weeks of gestation. RU-486 encloses FDA approved mifepristone. It executes abortion through mifepristone. Activity of Mifepristone is due to its structural similarity with progesterone. Mifepristone binds to progesterone’s receptors and decreases its concentration for the development of pregnancy. Progesterone supports pregnancy by making the uterine lining thick to support the embryo. In the absence of progesterone, uterine lining detaches the fetus from it leading in fetus death.
Three pills of mifepristone 200mg are kept inside a pack of Ru-486. For abortion, patient is supposed to take all the pills together with full glass of water orally. Bleeding with abdominal cramps will start within 4-5 hours of administration of pill. Onset of bleeding depends on the time and duration of pregnancy. After completion of menstrual flow, patient should go to doctor for medical checkup and ultrasound must be done for confirming the complete termination of pregnancy. In rare case, if bleeding not starts by taking mifepristone, then take 2 pills of misoprostol 200mcg and after bleeding, visit to doctor and get the ultrasound done.
Some side effects likely to occur with RU-486 are nausea, vomiting, stomach pain, abdominal cramps, drowsiness, Pelvic pain, gastro intestinal disturbances, pain in vagina etc.
Points to remember about use of RU-486:
RU-486 is only used if patient is not allergic from mifepristone. Avoid oily food and sexual relationships for some days after abortion. Take extra care if you are less than 18 years old. Use of RU-486 is not recommended if the female has an IUD. Avoid in case of bleeding disorders, anemia, kidney or liver disease. In case of ectopic pregnancy use of RU-486 is prohibited. When pregnancy is ectopic or intrauterine then use of abortion pills is not felt safe.
RU-486 can be purchased without prescription as it’s an OTC product. Get it from this approved drug portal at a genuine cost without paying extra shipping charges.